THE ACIDOSIS INDEX

The problems of acidosis.

After trauma the failure ofvarious organ functions tends to disturb acid-base equilibrium and produce acidaemia. Circulatory failure produces stagnation of blood in tissues and pulmonary failure, impairment of CO2 elimination and °2 uptake. Liver failure impairs the metabolic conversion of acid metabolites such as lactate or ketones into oxidizable substances and kidney failure impairs the excr...

Transcriptomic Changes in the Rumen Epithelium of Cattle after the Induction of Acidosis

The transition from normal forage to a highly fermentable diet to achieve rapid weight gain in the cattle industry can induce ruminal acidosis. The molecular host mechanisms that occur in acidosis are largely unknown. Therefore, the histology and transcriptome profiling of rumen epithelium was investigated in normal and acidosis animals to understand the molecular mechanisms involved in the dis...

The Nature of Diabetic Acidosis.

Lactic acidosis.

A 33-year-old male was admitted to Michael Reese Hospital and Medical Center for evaluation of weight loss, dyspnea, and fever. He had factor Vill-deficient hemophilia and had been chronically ill over several months with a cough productive of scanty sputum, weight loss of 15 Ibs, low-grade fever, and progressive dyspnea on exertion. The medical history was notable for right total hip replaceme...

Lactic Acidosis

Lactic acidosis is a form of metabolic acidosis due to the inadequate clearance of lactic acid from the blood. Lactate is a byproduct of anaerobic respiration and is normally cleared from the blood by the liver, kidney and skeletal muscle. Lactic acidosis occurs when the body's buffering systems are overloaded and tends to cause a pH of ≤7.25 with plasma lactate ≥5 mmol/L. It is usually caused ...